For a full story on sympathectomy and consequences, look up nerve injury or denervation

"I think the surgeons may not be aware of the long term consequences of denervation" Ahmet Hoke M.D., Ph.D. FRCPC

Professor of Neurology and Neuroscience, Director, Neuromuscular Division Johns Hopkins School of Medicine, Department of Neurology


Monday 27 April 2015

Post-sympathectomy neuralgia is proposed here to be a complex neuropathic and central deafferentation/reafferentation syndrome

The formation of the spinal nerve from the dor...
The formation of the spinal nerve from the dorsal and ventral roots. (Photo credit: Wikipedia)
 1996 Jan;64(1):1-9.

Post-sympathectomy neuralgia: hypotheses on peripheral and central neuronal mechanisms.

Abstract

Post-sympathectomy neuralgia is proposed here to be a complex neuropathic and central deafferentation/reafferentation syndrome dependent on: (a) the transection, during sympathectomy, of paraspinal somatic and visceral afferent axons within the sympathetic trunk; (b) the subsequent cell death of many of the axotomized afferent neurons, resulting in central deafferentation; and (c) the persistent sensitization of spinal nociceptive neurons by painful conditions present prior to sympathectomy. Viscerosomatic convergence, collateral sprouting of afferents, and mechanisms associated with sympathetically maintained pain are all proposed to be important to the development of the syndrome.

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